It is not known whether albumin is excreted in human milk. No human or animal data are available to indicate the presence or absence of drug-associated risk with albumin use while breast-feeding.
Exogenously administered albumin increases the oncotic pressure of the intravascular system, pulling fluids from the interstitial space, thereby decreasing edema and increasing the circulating blood volume. This increase in volume reduces the concentration and viscosity of blood in patients with decreased circulating blood volume and also maintains cardiac output in shock.
In dehydrated patients, albumin has little or no clinical effect on circulating blood volume. Albumin is also used to replace protein in patients with hypoproteinemia until the cause of the deficiency can be determined. It is distributed only in the intravascular space. Albumin solutions have a plasma half-life of 16 to 24 hours and a duration of volume expansion of 12 to 24 hours. When administered to patients with diminished blood volume, the effect of infused albumin may last for many hours; however, the duration is much shorter in patients with normal blood volume.
In a kg patient, total blood albumin is approximately g. PDR Search. Required field. Your Name Your name is required. Recipient's Email Separate multiple email address with a comma Please enter valid email address Recipient's email is required. Thank you. Your email has been sent. Jump to Section.
Related Drug Information Drug Summary. Infants and Children. For the treatment of acute nephrosis in nephrotic syndrome. For third space protein loss due to infection. Children and Adolescents. For adjunctive use with exchange transfusion in the treatment of hyperbilirubinemia and erythroblastosis fetalis hemolytic disease of the newborn.
For use during cardiopulmonary bypass surgery, including pump priming. Infants, Children, and Adolescents. For the treatment of acute respiratory distress syndrome ARDS. For the prevention of central volume depletion after paracentesis due to ascites in hepatic cirrhosis. Maintenance of plasma colloid osmotic pressure and carriage of intermediated products in the transport and exchange of tissue metabolites. Maintenance of plasma colloid osmotic pressure and carriage of intermediate products in the transport and 3exchange of tissue metabolites.
Use in patients with fluid or sodium restrictions e. Albumin is a plasma-derived blood product. Albumin may be prescribed as a bolus dose, where a patient requires an Albumin infusion over a discrete period of time and the total dose is known. A continuous infusion is sometimes used when a patient needs an Albumin infusion for an extended period of time and when the clinician does not know exactly when the infusion will cease. In this instance it should be prescribed as a regular administration e.
Two clinicians must independently complete the patient and blood product identification check at the bedside. Record the batch number and expiry date of each bottled infused in the medical record.
Staff administering Albumin must also record the date, time and volume infused. Administer via a standard intravenous IV giving set.
It does not require a transfusion filter. The manufacturer recommends that each bottle of Albumin is used immediately after opening the bottle as it does not contain antimicrobial preservative. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
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